Why is Proper Storage Important?
Peptides such as semaglutide, retatrutide, and tirzepatide are sensitive proteins. Incorrect storage can degrade the molecules, rendering them ineffective or even harmful. Proper storage ensures that your peptide retains its full potency.
Storage of Unopened/Unmixed Peptides
Lyophilized peptides (powder form):
- Best: Refrigerator (2-8°C) - lasts 2+ years
- Acceptable: Room temperature below 25°C - lasts 3-6 months
- Avoid: Heat above 25°C and direct sunlight
Unopened, lyophilized peptides are relatively stable. They can be stored in a refrigerator for several years without significant loss of potency.
Storage of Mixed/Reconstituted Peptides
This is critical! Once the peptide is mixed with bacteriostatic water, it becomes much more sensitive.
Mixed peptides MUST be stored in a refrigerator:
- Temperature: 2-8°C (normal refrigerator temperature)
- Shelf life: 28-30 days
- Placement: Deep inside the refrigerator, not in the door
Why not in the refrigerator door?
The temperature in the door fluctuates more when the refrigerator is opened and closed. Place the vial deep inside where the temperature is most stable.
Shelf Life by Peptide Type
| Peptide | Unopened | Mixed |
|---|---|---|
| Semaglutide | 2+ years (refrigerator) | 28-30 days |
| Retatrutide | 2+ years (refrigerator) | 28-30 days |
| Tirzepatide | 2+ years (refrigerator) | 28-30 days |
Can Peptides Be Frozen?
Unopened peptides:
Yes, lyophilized peptides can be stored in a freezer (-20°C) for even longer shelf life. Allow them to reach refrigerator temperature before opening to avoid condensation.
Mixed peptides:
No! Never freeze an already mixed peptide. Freezing and thawing can destroy the protein structure, making the peptide ineffective.
Signs of Peptide Degradation
Always check your peptide before use. Signs of degradation:
- Cloudy solution - Should be completely clear
- Particles or flakes - Indicates aggregation
- Changed color - Should be colorless
- Strange odor - Should be odorless
If you notice any of the above, discard the peptide and use a new one.
What Happens if the Peptide Gets Warm?
Short-term exposure (a few hours under 30°C):
Likely okay, but may have lost some potency. Use with caution.
Longer exposure or higher temperatures:
The peptide may have degraded. It is recommended to discard and use a new one.
Tips for transport:
- Use a cooler bag with ice packs
- Avoid leaving in a hot car
- Do not order during extremely hot periods
Storage During Travel
If traveling with your peptides:
- Short trip (1-2 days): A cooler bag with an ice pack is often sufficient
- Longer trip: Ensure you have access to a refrigerator
- Air travel: Keep in carry-on luggage (cargo hold may get too cold)
Checklist for Proper Storage
- ☐ Always store mixed peptides in the refrigerator (2-8°C)
- ☐ Place deep inside the refrigerator, not in the door
- ☐ Protect from direct light
- ☐ Write the mixing date on the vial
- ☐ Use within 30 days after mixing
- ☐ Check that the solution is clear before each use
- ☐ Never freeze mixed peptides
Summary
Proper storage is crucial for your peptide to maintain its effectiveness. Remember: refrigerate mixed peptides, use within 30 days, and always check that the solution is clear before use. With proper storage, you get the maximum value from your investment.