📑 Contents
What is Semaglutide?
Semaglutide is a GLP-1 receptor agonist originally developed for the treatment of type 2 diabetes. The substance has proven to be extremely effective for weight loss and is now used worldwide for this purpose.
💡 What is GLP-1?
GLP-1 (glucagon-like peptide-1) is a hormone naturally produced in the intestine after meals. Semaglutide mimics this hormone and enhances its effects.
Semaglutide provides several positive effects:
- Reduced appetite — You feel full faster and for longer
- Slower gastric emptying — Food stays in the stomach longer
- Improved blood sugar control — More stable energy levels
- Reduced reward feeling from food — Less craving for unhealthy food
How does Semaglutide work for weight loss?
📊 Clinical Results
In the STEP studies, participants showed an average weight loss of 15-17% of body weight over 68 weeks — equivalent to about 15-20 kg for a person weighing 100 kg.
Semaglutide acts in several ways simultaneously:
- Hypothalamus — Affects the brain's hunger center and naturally reduces appetite
- Stomach — Slows down emptying, providing longer satiety after meals
- Pancreas — Improves insulin release and stabilizes blood sugar
Semaglutide Dosage — Titration Schedule
⚠️ Important
Always start with a low dose and increase gradually. Skipping steps significantly increases the risk of side effects.
Common Side Effects
Most side effects are mild and subside after a few weeks:
- Nausea — Most common in the first weeks, usually subsides
- Diarrhea or constipation — Temporary gastrointestinal issues
- Headache — Typically disappears after the adjustment period
- Fatigue — May occur initially
- Reduced appetite — Desired effect but may feel unusual
💡 Tips to Reduce Side Effects
- Eat smaller portions and eat slowly
- Avoid fatty and spicy foods initially
- Drink plenty of water (at least 2 liters/day)
- Take the injection in the evening if nausea is bothersome
How is Semaglutide Stored?
Proper storage is crucial to maintain the peptides' effectiveness:
| Condition | Temperature | Shelf Life |
|---|---|---|
| Unopened (lyophilized) | 2-8°C (refrigerator) | 12-24 months |
| After mixing | 2-8°C (refrigerator) | 28-30 days |
| Room temperature | 15-25°C | Max a few hours |
🚫 Never Freeze!
Freezing permanently destroys the peptide structure. Also protect from direct light.
How to Mix Semaglutide?
If you purchase lyophilized (freeze-dried) Semaglutide, you need to mix it with bacteriostatic water:
- Prepare — Clean the rubber stopper on both vials with an alcohol swab
- Draw water — Draw the desired amount of BAC water into the syringe (recommended: 2ml)
- Add gently — Inject the water along the glass wall — never spray directly onto the powder
- Mix — Gently swirl the vial — never shake!
- Wait — Allow the powder to dissolve completely (may take a few minutes)
📖 Read our detailed mixing guide →
Price Comparison
| Product | Type | Approximate Price/Month |
|---|---|---|
| Ozempic | Prescription | ~1500-2500 SEK |
| Wegovy | Prescription | ~2000-3000 SEK |
| Research Peptides | Research | Significantly lower |
Who Should Use Semaglutide?
✓ May be suitable for those who:
- Have a BMI over 30 (obesity)
- Have a BMI over 27 with weight-related health issues
- Have tried diet and exercise without sufficient effect
- Do not have contraindications (see below)
✗ Do NOT use if you have:
- Personal or family history of medullary thyroid carcinoma
- MEN 2 (multiple endocrine neoplasia type 2)
- Severe kidney or liver disease
- Pregnancy or breastfeeding
- Severe gastrointestinal diseases
Frequently Asked Questions about Semaglutide
How quickly will results be seen?
Most notice a reduced appetite in the first week. Visible weight loss usually begins after 4-8 weeks. Maximum effect is typically achieved after 4-6 months on the full dose.
Do you need to exercise simultaneously?
Semaglutide works even without exercise, but the combination yields better results and helps preserve muscle mass during weight loss.
Can you stop once you've reached your target weight?
Research shows that weight often returns if you stop completely. Many choose to continue on a lower maintenance dose.
Is it safe long-term?
Studies up to 2 years show a good safety profile. Long-term studies are still ongoing.
Summary
Semaglutide is a powerful tool for weight loss that works by reducing appetite and improving the body's metabolism. With the right dosage, proper storage, and realistic expectations, it can help many achieve their weight goals.
⚠️ Research Disclaimer
All peptides we sell are intended for research purposes only. Always consult a physician before starting any treatment.