📑 Contents
Why is Titration Important?
⚠️ Common Mistake
Starting with the full dose immediately can lead to unnecessarily severe side effects. The body needs time to adjust to GLP-1 stimulation.
Gradual titration provides:
- Fewer side effects — Especially nausea and gastrointestinal issues
- Better tolerance — The body gradually adapts
- Sustainable results — You can complete the treatment
Standard Dosage Schedule
Dose Calculation with Insulin Syringe
If you have mixed 5mg Semaglutide in 2ml BAC water:
| Desired Dose | Syringe Units | Period |
|---|---|---|
| 0.25 mg | 10 units | Week 1-4 |
| 0.5 mg | 20 units | Week 5-8 |
| 1.0 mg | 40 units | Week 9-12 |
| 1.7 mg | 68 units | Week 13-16 |
| 2.4 mg | 96 units | Week 17+ |
📖 Read how to mix Semaglutide →
When Should You Take Your Dose?
📅 Dosage Once a Week
- Choose a day that fits your routine (e.g., every Sunday)
- Take the injection at the same time each week
- Can be taken with or without food
Tips to Remember:
- Set an alarm on your phone
- Link it to a weekly event
- Use a medication app
If You Miss a Dose:
- Within 5 days: Take the dose as soon as you remember
- More than 5 days: Skip it and take the next dose on your usual day
- Never double the dose!
When Should You Stay on a Dose Longer?
⚠️ Do NOT Increase the Dose if You Experience:
- Severe nausea that doesn't subside
- Recurrent vomiting
- Severe diarrhea or constipation
- Intense abdominal pain
Stay on the current dose for 1-2 extra weeks until the side effects decrease.
Maintenance Dose — After Target Weight
Once you have achieved the desired weight loss, there are several options:
✓ Option 1: Continue at Full Dose
Best for maintaining maximum effect.
💡 Option 2: Reduce to Maintenance Dose
Many manage to maintain their weight on 1.0-1.7 mg.
💡 Option 3: Gradual Tapering
If you wish to stop, taper down over 8-12 weeks.
📊 Research Shows
Most regain weight within 1 year if they stop completely without lifestyle changes.
Frequently Asked Questions About Dosage
Can I Increase Faster if I Have No Side Effects?
It is not recommended. Even if you tolerate low doses well, higher doses can cause issues. Follow the schedule.
What Happens if I Take Too Much?
Overdose can cause severe nausea, vomiting, and low blood sugar. Seek medical attention if severe symptoms occur.
Does It Matter Where I Inject?
Recommended areas: abdomen (at least 5 cm from the navel), thigh (front middle), upper arm (back). Rotate injection site each week.
Summary
✓ Remember
- Always start at 0.25 mg
- Increase every 4 weeks according to the schedule
- Stay longer on a dose if experiencing troublesome side effects
- Take on the same day and time each week
- Discuss maintenance dose when you reach your goal